Evidence supporting the use of: Rutin
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rutin is a bioflavonoid found in various plants, known for its antioxidant and vasoprotective properties. Its use in supporting eye health is primarily based on its ability to strengthen capillaries and reduce oxidative stress, both of which are relevant to eye health, particularly in conditions like diabetic retinopathy and other microvascular disorders. Several laboratory and animal studies indicate that rutin can help protect retinal cells from oxidative damage and may support vascular integrity in the eye. For example, some research shows that rutin supplementation reduces retinal oxidative stress and protects against experimentally induced retinal injury in animal models.

However, clinical evidence in humans is limited. While small studies and historical use suggest potential benefits in reducing capillary fragility and microbleeds, robust randomized controlled trials specifically examining rutin for eye health or diseases such as macular degeneration or diabetic retinopathy are lacking. Its inclusion in some eye health supplements is often based on extrapolation from its general vascular and antioxidant benefits rather than direct, high-quality clinical evidence for ocular outcomes. In summary, the scientific rationale exists, but the strength of evidence in humans remains modest, warranting a rating of 2 out of 5.

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Other ingredients that support Eyes

3,3'-dihydroxy-B-carotene-4,4'-dione
Acetyl L-carnitine
Alchornea
Algae
algal oil
Alpha-carotene
anchovies
anthocyanidins
anthocyanins
anthocyanosides
apricot
Aronia melanocarpa
astaxanthin
avocado
barbary matrimony vine
bee products
Beef liver
berry
beta-carotene
beta-zeacarotene
bilberry
bioflavonoids
black currant
blackberry
Blakeslea trispora
blueberry
broccoli
calamari oil
cantaloupe
capsanthin
Carnosine
carotene (unspecified)
carrot
Celosia
chickweed
Chinese Ligustrum berry
chrysanthemum
citicoline
cocklebur
cod liver oil
cornflower
Cornus
crocetin
crocin
Crypthecodinium
cryptoxanthin
currant
cyanidin
d-alpha tocopherol
DHA (docosahexaenoic acid)
docosahexaenoic Acid
Dunaliella
Dunaliella salina
egg
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
ergothioneine
Eyebright
Fagopyrum
fat liver oil
fatty acids
fibroblast growth factor
fish
fish oil
flavoglycosides
flavonoids
flavonols
fruit
fruit and vegetable blend (proprietary)
Gac
gamma-carotene
ginkgo flavone glycoside
Glutathione
goji berry
gooseberry
Haematococcus pluvialis
haliotis
herbal blend (proprietary)
huckleberry
hyaluronic acid
Idebenone
kale
L-carnosine
L-taurine
Ligustrum
lipids
lutein
Lycium
marigold
Marine fat
Marine lipid
Melatonin
Mineral ascorbate
mixed carotenoids
Morus
Mulberry
N-Acetyl Carnosine
Oligomeric proanthocyanidins
omega-3 fatty acids
orange
Phaffia rhodozyma
pine bark
Polygonum
polyphenols
polyunsaturated fat
proanthocyanidins
procyanidol
pumpkin
Pycnogenol
riboflavin (vitamin B2)
rose
rue
rutin
saffron
Salmon Oil
Schizochytrium
Schizochytrium Oil
Spanish Needle
spinach
Tagetes
Taurine
Tea
trace minerals
Triphala
Troxerutin
vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
Xanthophyll
Zeaxanthin
Zinc

Other body systems supported by rutin

Arteries
Blood
Capillaries
Circulatory System
Eyes
Heart
Veins