Evidence supporting the use of: Rutin
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rutin is a bioflavonoid found in various plants, known for its antioxidant and vasoprotective properties. Its use in supporting eye health is primarily based on its ability to strengthen capillaries and reduce oxidative stress, both of which are relevant to eye health, particularly in conditions like diabetic retinopathy and other microvascular disorders. Several laboratory and animal studies indicate that rutin can help protect retinal cells from oxidative damage and may support vascular integrity in the eye. For example, some research shows that rutin supplementation reduces retinal oxidative stress and protects against experimentally induced retinal injury in animal models.

However, clinical evidence in humans is limited. While small studies and historical use suggest potential benefits in reducing capillary fragility and microbleeds, robust randomized controlled trials specifically examining rutin for eye health or diseases such as macular degeneration or diabetic retinopathy are lacking. Its inclusion in some eye health supplements is often based on extrapolation from its general vascular and antioxidant benefits rather than direct, high-quality clinical evidence for ocular outcomes. In summary, the scientific rationale exists, but the strength of evidence in humans remains modest, warranting a rating of 2 out of 5.

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