Evidence supporting the use of: Pine bark
For the body system: Eyes
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Pine bark extract, specifically Pycnogenol® (a standardized extract from the bark of the French maritime pine, Pinus pinaster), has been investigated for its potential benefits in supporting eye health, particularly in relation to retinal microcirculation and diabetic retinopathy. Several clinical studies have reported that supplementation with pine bark extract may improve retinal blood flow and reduce the progression of early-stage diabetic retinopathy. The proposed mechanisms include its potent antioxidant properties, its ability to enhance endothelial function, and its role in reducing capillary permeability and inflammation.
For example, a randomized, placebo-controlled study published in Diabetes Research and Clinical Practice (2007) found that 150 mg/day of Pycnogenol® for three months improved retinal edema and visual acuity in patients with mild to moderate diabetic retinopathy. Other studies have observed similar benefits, including improved microcirculation in the retina and reduced symptoms of eye fatigue. However, while these results are promising, the overall body of evidence is limited by small sample sizes and the need for more robust, long-term clinical trials.
In summary, there is scientific evidence—though not yet conclusive—that pine bark extract may support eye health, especially in conditions involving microvascular dysfunction. Its use for general eye support is not rooted in traditional herbal medicine but is rather based on recent clinical research.
Other ingredients that support Eyes
acetyl l-carnitinealgal oil
alpha-carotene
anchovies
anthocyanins
apricot
astaxanthin
berry flavor
beta-carotene
bilberry
black currant
blackberry
blueberry
broccoli
calamari oil
carrot
citicoline
cryptoxanthin
d-alpha tocopherol
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flavonols
fruit and vegetable blend (proprietary)
gooseberry
hyaluronic acid
hypromellose
kale
l-carnosine
l-taurine
lutein
mackerel
mannitol
marine lipid
melatonin
mixed carotenoids
omega-3 fatty acids
orange
pine bark
pumpkin
riboflavin (vitamin B2)
rutin
saffron
sardines
shrimp
spinach
tomato
triphala
vegetable and fruit blend (proprietary)
vitamin A
vitamin B
vitamin C
vitamin E
water
mulberry
zeaxanthin
zinc
chickweed
morus
chrysanthemum
haliotis
polyphenols
trace minerals
goji berry
herbal blend (proprietary)
algae
3,3'-dihydroxy-B-carotene-4,4'-dione
Aronia melanocarpa
Alchornea
Avocado
anthocyanidins
anthocyanosides
beta-zeacarotene
Beef liver
Blakeslea trispora
berry
Bioflavonoids
Bee products
Barbary matrimony vine
Crocin
Carnosine
Cod Liver Oil
Cyanidin
Cornflower
Cantaloupe
Chinese Ligustrum berry
Cornus
Carotene (unspecified)
Crocetin
Cocklebur
Crypthecodinium
Celosia
Capsanthin
Currant
Dunaliella salina
Docosahexaenoic Acid
Dunaliella
Egg
Ergothioneine
Eicosapentaenoic Acid
Flavonoids
fibroblast growth factor
Rose
Squid
Squash
Other body systems supported by pine bark
ArteriesBlood
Brain
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Joints
Skin
Veins
Products containing pine bark
Nature's Sunshine High Potency Grapine
Nature's Sunshine Grapine With Protectors (SynerPro)