Evidence supporting the use of: Lutein
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lutein is a carotenoid found in high concentrations in leafy green vegetables and is a major component of the macular pigment in the human retina. Scientific interest in lutein for eye health is primarily due to its antioxidant properties and its role in filtering high-energy blue light, which may help protect retinal tissue from oxidative stress and light-induced damage. Several observational studies have reported that higher dietary intake of lutein is associated with a reduced risk of age-related macular degeneration (AMD) and cataracts. Interventional studies, including randomized controlled trials such as the AREDS2 (Age-Related Eye Disease Study 2), have evaluated the impact of lutein supplementation on the progression of AMD. Results have indicated that supplementation with lutein (often in combination with zeaxanthin) can modestly slow the progression of intermediate to advanced AMD in some individuals, particularly those with low dietary intake of these carotenoids. However, the evidence is not uniformly strong, as some studies show limited or no benefit. The overall scientific consensus supports a modest but real benefit of lutein supplementation in supporting eye health, especially in populations at risk for AMD, though it is not considered a cure or a primary treatment. The evidence supporting lutein’s use for general eye health is stronger than for many other supplements, but the effect size is moderate.

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Other body systems supported by lutein

Brain
Eyes
Senses