Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fibroblast growth factors (FGFs) are a family of proteins involved in a wide range of biological processes, including cell growth, tissue repair, and angiogenesis. In the context of the eye, scientific research has demonstrated that FGFs play a significant role in ocular development, maintenance, and healing. For example, FGF-2 (basic FGF) is highly expressed in the retina and has been shown to protect retinal neurons from damage, promote regeneration of retinal tissue, and support corneal wound healing. Experimental studies, particularly in animal models, have provided evidence that topical or intraocular administration of FGFs can accelerate corneal epithelial repair and may help preserve retinal function in degenerative conditions.

However, while preclinical studies are promising, robust clinical trials in humans are limited. Some early-phase studies and case reports suggest beneficial effects, especially for corneal injuries and possibly in certain retinal diseases, but FGFs are not yet a standard therapy for ocular conditions in mainstream medicine. The evidence is strongest in the context of wound healing and tissue repair rather than for general eye health. Thus, the use of fibroblast growth factors to support the eye is supported by scientific research, though most of the evidence comes from laboratory and animal studies, and more clinical research is needed to fully validate their therapeutic potential in human eye diseases.

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