Evidence supporting the use of: Fatty Acid (unspecified)
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Fatty acids, particularly omega-3 polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have significant scientific backing for their role in supporting the health of the eyes. Numerous clinical studies have demonstrated that omega-3 fatty acids contribute to the structural integrity of the retina and play a role in visual development and function. A notable body of research, including large randomized controlled trials like the Age-Related Eye Disease Study 2 (AREDS2), has examined the potential of omega-3 supplementation in slowing the progression of age-related macular degeneration (AMD), one of the leading causes of vision loss in older adults. While some studies suggest a modest benefit in reducing the risk or progression of AMD and alleviating symptoms of dry eye disease, results have been somewhat mixed, with some meta-analyses indicating only marginal effects. Nonetheless, the biological plausibility is strong, as DHA is a major structural component of retinal photoreceptors. Additionally, omega-3 fatty acids possess anti-inflammatory properties that may help protect ocular tissues. Therefore, the use of unspecified fatty acids for eye health is mainly justified when referring to specific fatty acids like EPA and DHA, with moderate to strong scientific evidence supporting their benefit for certain eye conditions.

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