Evidence supporting the use of: Bioflavonoids
For the body system: Eyes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bioflavonoids, a group of plant-derived compounds also known as flavonoids, have been studied for their antioxidant properties and potential benefits to eye health. Scientific interest in bioflavonoids for ocular support primarily stems from their ability to neutralize free radicals and reduce oxidative stress, which is implicated in the pathogenesis of various eye conditions, such as age-related macular degeneration (AMD) and cataracts. Some epidemiological studies have suggested that higher intake of flavonoid-rich foods may be associated with a reduced risk of certain eye diseases. For example, flavonoids such as quercetin, rutin, and hesperidin have shown protective effects on retinal cells in laboratory and animal studies, mainly through antioxidative and anti-inflammatory mechanisms.

However, while these findings are promising, clinical evidence in humans remains limited and inconsistent. Most studies have evaluated specific flavonoids rather than unspecified "bioflavonoids," and results vary depending on the type and dosage of the compound tested. Major eye health organizations do not currently recommend bioflavonoid supplementation as a standard therapy for eye diseases, though they recognize the potential of a flavonoid-rich diet. In summary, there is some scientific rationale and preliminary evidence supporting the use of certain bioflavonoids for eye health, but robust clinical validation is lacking, especially for unspecified mixtures.

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