Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanosides, flavonoid compounds found primarily in bilberry (Vaccinium myrtillus) and other berries, have been traditionally used to support eye health, particularly in Europe. The interest in their use for eye problems, such as night vision and retinal disorders, stems from claims that British pilots in World War II experienced improved night vision after consuming bilberry jam. Subsequently, anthocyanosides have been investigated for their antioxidant properties, ability to strengthen capillaries, and potential effects on ocular tissues.

Scientific studies have explored anthocyanosides' effects on visual function and eye health. Some small clinical trials and animal studies indicate that these compounds may help improve microcirculation in the retina and protect against oxidative stress, which is relevant to conditions like diabetic retinopathy and macular degeneration. However, results are mixed and often limited by small sample sizes, short durations, and methodological weaknesses. For example, a systematic review published in Ophthalmic & Physiological Optics (2012) concluded that while there is some evidence for improved subjective night vision, there is insufficient high-quality evidence to support significant clinical benefits in eye diseases.

In summary, there is some scientific rationale and preliminary evidence supporting the use of anthocyanosides for certain eye problems, but robust clinical validation is lacking. The evidence is suggestive but not conclusive, warranting a moderate-low evidence rating.

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