Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Anthocyanidins are a class of flavonoids responsible for the red, purple, and blue pigments in many fruits and vegetables, notably in berries and grapes. Their use in supporting or treating eye problems, especially conditions like night vision impairment and age-related macular degeneration (AMD), is primarily based on their antioxidant properties. Some scientific studies, particularly those focusing on bilberry (rich in anthocyanidins), have suggested potential benefits for retinal health and visual function. For example, in vitro and animal studies indicate that anthocyanidins may protect retinal cells from oxidative stress and improve microcirculation in ocular tissues.

However, human clinical evidence remains limited and mixed. Early anecdotal reports and small studies—some dating back to World War II—suggested that pilots consuming bilberry jam experienced improved night vision, but subsequent controlled trials have not consistently supported these claims. More recent systematic reviews and meta-analyses have concluded that while anthocyanidin-rich extracts may offer some protective effects against oxidative damage in the eye, robust clinical evidence for their effectiveness in treating or preventing specific eye diseases is lacking. Larger, well-designed trials are still needed.

In summary, while there is a scientific rationale for the use of anthocyanidins in eye health due to their antioxidant effects, current evidence from human studies is not strong, and the rating of evidence is low (2 out of 5).

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