Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) commonly used in ophthalmology, but not directly as an antimicrobial agent for treating eye infections. Its primary indication in eye care is to reduce inflammation and pain, often after ocular surgery (e.g., cataract extraction) or to manage conditions like postoperative cystoid macular edema. Diclofenac ophthalmic preparations can help alleviate symptoms such as redness, swelling, and discomfort associated with various ocular surface inflammations, which may sometimes accompany infectious processes.

There is moderate scientific evidence (rated 3/5) supporting the use of diclofenac in the context of eye infections, but only as an adjunct for symptom control, not as a treatment for the infection itself. Clinical studies and guidelines suggest that while diclofenac can help control inflammation and pain associated with infectious conjunctivitis or keratitis, it should not replace antimicrobial therapy. In fact, unmonitored use in the presence of corneal ulcers or active infection can increase the risk of complications, such as delayed healing or corneal melting. Thus, the use of diclofenac in eye infections is scientifically justified only for symptom management under close supervision and always alongside appropriate antimicrobial treatment.

In summary, diclofenac is not an anti-infective agent but has a supportive role in managing pain and inflammation in some infectious eye conditions, provided that effective antimicrobial therapy is also employed.

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