Evidence supporting the use of: Centipeda minima
For the health condition: Eye Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Centipeda minima, commonly known as spreading sneezeweed or "Eclipta," has a long history of use in traditional Chinese medicine (TCM) and some other Asian traditional medicine systems. In TCM, it is called "Xiao Bai Ju" and is used for various purposes, including the treatment of eye infections and disorders such as conjunctivitis. The rationale for its use is based on its traditional classification as an herb that "disperses wind-heat" and "detoxifies," which are believed to correspond to reducing inflammation and infection in TCM theory.

Phytochemical studies show that Centipeda minima contains flavonoids, sesquiterpene lactones, and volatile oils with reported anti-inflammatory and antimicrobial activities [1]. Some in vitro studies suggest modest antibacterial effects, but there is limited direct scientific research validating its effectiveness specifically for eye infections in humans. No rigorous clinical trials exist that evaluate its safety and efficacy for ocular conditions. Thus, the use of Centipeda minima for eye infections remains primarily supported by traditional use and anecdotal reports, rather than by modern scientific validation.

References:
[1] Gong, G. et al. (2013). "Phytochemistry and pharmacology of Centipeda minima: a review." Phytotherapy Research, 27(11): 1589–1595.
"Chinese Herbal Medicine: Materia Medica" (Bensky, Clavey, Stöger, 3rd ed.)

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