Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Somatropin is a synthetic form of human growth hormone (hGH) used primarily for conditions involving growth hormone deficiency, but it has also been used off-label in the context of exercise and athletic performance. Scientific evidence shows that somatropin increases lean body mass and decreases fat mass, which has made it attractive to some athletes and bodybuilders. However, while somatropin does improve body composition, well-controlled studies indicate that it does not significantly enhance muscle strength, aerobic capacity, or actual exercise performance in healthy individuals (Liu et al., Ann Intern Med, 2008). Additionally, the use of somatropin for exercise enhancement is not approved by regulatory agencies, and it is banned by most sports organizations due to potential side effects such as joint pain, insulin resistance, and increased risk of diabetes.

Historically, somatropin’s use in exercise contexts has been driven by anecdotal reports and its muscle-building reputation rather than robust scientific validation. The evidence supporting its use for improving exercise performance or recovery is weak, with most benefits limited to changes in body composition rather than objective improvements in athletic capabilities. Thus, while there is some scientific investigation into somatropin’s effects on exercise-related outcomes, the overall evidence for its effectiveness in this context is limited and does not justify its use for this purpose outside of specific medical indications.

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