Evidence supporting the use of: Elthyl-Alpha-Guanido-Methyl-Ethanoate
For the health condition: Exercise

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Ethyl-Alpha-Guanido-Methyl-Ethanoate is the systematic chemical name for creatine ethyl ester, a derivative of creatine. Creatine, in its various forms, is widely used as a dietary supplement to enhance exercise performance, particularly in activities that involve short bursts of high-intensity effort such as weightlifting and sprinting. Scientific studies have consistently demonstrated that creatine monohydrate supplementation increases intramuscular phosphocreatine stores, which in turn supports rapid regeneration of adenosine triphosphate (ATP), the primary energy currency in muscle cells during intense activity.

While traditional creatine monohydrate is the most studied and validated form, creatine ethyl ester has been marketed as a potentially more bioavailable version. However, research directly comparing creatine ethyl ester to creatine monohydrate has shown that the former does not offer superior benefits and, in some cases, may be less effective at elevating muscle creatine content. Nonetheless, the general scientific consensus affirms that creatine supplementation (regardless of form) supports improved exercise performance, increased strength, and enhanced muscle mass gains in response to training.

Overall, the evidence base for creatine's effectiveness in supporting exercise is robust (rating: 4/5), though creatine monohydrate is preferred over ethyl ester due to better absorption and efficacy profiles. The use of creatine ethyl ester is justified by scientific evidence related to creatine’s role in exercise, but not specifically by the ethyl ester variant.

More about Elthyl-Alpha-Guanido-Methyl-Ethanoate
More about Exercise

Other health conditions supported by Elthyl-Alpha-Guanido-Methyl-Ethanoate

Athletic and Exercise Aids
Body Building
Endurance (lack of)
Energy (lack of)
Exercise
Fatigue

Products containing Elthyl-Alpha-Guanido-Methyl-Ethanoate

We currently have no products on Caring Sunshine that contain this ingredient.