Evidence supporting the use of: Cordyceps
For the health condition: Exercise

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cordyceps, a genus of fungi, has been traditionally used in Chinese medicine for centuries, particularly to enhance stamina and combat fatigue. In recent years, its potential role in improving exercise performance has attracted scientific interest. Several small-scale, randomized controlled trials and animal studies have explored its effects on aerobic capacity, endurance, and fatigue resistance.

The scientific evidence is mixed. Some studies suggest that supplementation with Cordyceps sinensis or its cultivated counterpart, Cordyceps militaris, may modestly increase VO2 max (a measure of aerobic capacity) and reduce fatigue during exercise, possibly due to its effects on ATP production and enhanced oxygen utilization. A few human studies reported improved exercise performance or reduced time to fatigue in older adults or less fit individuals, but results in trained athletes are inconsistent or show minimal benefit. Additionally, most studies have small sample sizes, short durations, and sometimes lack rigorous blinding or placebo control.

Mechanistically, the potential benefits are thought to arise from bioactive compounds such as cordycepin and polysaccharides, which may enhance mitochondrial function and possess antioxidant properties. However, more large-scale, well-designed clinical trials are needed to confirm these findings and establish effective dosing.

In summary, scientific support for Cordyceps in exercise enhancement is emerging but not robust, earning it a moderate evidence rating. It is most promising for general fatigue and mild improvements in exercise capacity rather than dramatic performance gains in athletes.

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