Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Arachidonic acid (AA) is a polyunsaturated omega-6 fatty acid involved in cellular signaling and inflammation. Its use as a supplement to support exercise performance, muscle growth, and recovery is based on its role as a precursor to prostaglandins, which are involved in the muscle repair and growth processes following resistance exercise. Some small, short-term studies suggest that AA supplementation may enhance muscle hypertrophy and strength gains in resistance-trained individuals. For example, a randomized controlled trial by Roberts et al. (2007) found that 1,000 mg/day of AA supplementation for 50 days increased lean body mass and strength more than placebo in trained men. However, the effect size was modest and results have not been widely replicated.

Other studies have either not found significant benefits or have raised concerns about potential pro-inflammatory effects and the long-term safety of increasing AA intake, given its role in producing pro-inflammatory eicosanoids. The overall body of evidence is limited, with few high-quality, long-term studies, and most research has been conducted in healthy, resistance-trained young men. As such, while there is some scientific evidence supporting the use of AA for exercise-related outcomes, it is not strong or conclusive, justifying a rating of 2/5.

More about arachidonic acid
More about Exercise

Other ingredients used for Exercise

Other health conditions supported by arachidonic acid

Products containing arachidonic acid