Evidence supporting the use of: Progesterone
For the body system: Estrogen

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Progesterone is scientifically validated as an essential hormone in the estrogen-progesterone balance within the female reproductive system. It is commonly used in hormone replacement therapy (HRT) for women, particularly during menopause or for those with estrogen dominance. Progesterone's role is to counterbalance the proliferative effects of estrogen on the endometrium, thus reducing the risk of endometrial hyperplasia and carcinoma in women receiving estrogen therapy (Stanczyk et al., 2013). Clinical guidelines strongly recommend the addition of progesterone or a progestin for women with a uterus who are undergoing estrogen therapy.

Furthermore, progesterone is crucial in regulating the menstrual cycle and maintaining pregnancy. Its supplementation is also indicated in certain forms of infertility and in the management of specific menstrual disorders. Multiple randomized controlled trials and systematic reviews confirm its efficacy and safety in these settings (Lobo, 2012). However, the evidence is less robust for "bioidentical" progesterone creams or over-the-counter preparations that are sometimes marketed for generalized hormone balance.

In summary, progesterone is routinely used in evidence-based medical practice to support the estrogen body system, with substantial scientific backing primarily in the context of endometrial protection during estrogen therapy and reproductive health.

More about Progesterone
More about Estrogen

Products containing Progesterone

We currently have no products on Caring Sunshine that contain this ingredient.