Evidence supporting the use of: Bacillus coagulans
For the health condition: Enteritis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bacillus coagulans is a probiotic bacterium that has garnered attention for its potential role in managing various gastrointestinal disorders, including enteritis. Enteritis, defined as inflammation of the small intestine, can be caused by infections, medications, or autoimmune conditions. The use of B. coagulans for enteritis is supported by several scientific studies, though the evidence is moderate rather than conclusive.

Research suggests that B. coagulans can help modulate the gut microbiota, improve the intestinal barrier, and reduce inflammation. Its spores are resistant to gastric acid, allowing the bacterium to reach the intestine alive, where it can exert its probiotic effects. Clinical trials have shown that B. coagulans supplementation may reduce symptoms such as diarrhea, abdominal pain, and bloating, which are common in enteritis and related conditions. For example, randomized controlled trials (RCTs) in patients with irritable bowel syndrome and antibiotic-associated diarrhea—conditions that share some pathophysiological features with enteritis—have demonstrated symptom improvement with B. coagulans supplementation.

Mechanistically, B. coagulans produces lactic acid and short-chain fatty acids, which help suppress pathogenic bacteria and promote mucosal healing. However, while these findings are promising, direct clinical studies specifically targeting enteritis are limited. Most evidence is extrapolated from broader studies on gastrointestinal health or related inflammatory conditions. Thus, while scientific rationale and some supportive evidence exist, more targeted research is needed to firmly establish B. coagulans as a treatment for enteritis.

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