Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin B5, also known as pantothenic acid, plays a crucial role in the body’s energy metabolism as a component of coenzyme A, which is essential for the synthesis and oxidation of fatty acids and the Krebs (citric acid) cycle. This biochemical role is well-established in scientific literature, and deficiencies in B5 can lead to symptoms such as fatigue, apathy, and malaise due to impaired energy production. However, frank deficiency is rare in humans because pantothenic acid is widely available in foods.

Clinical evidence supporting the use of vitamin B5 supplementation for improving energy levels in otherwise healthy individuals is limited. Most research has focused on deficiency states or animal models. There is a lack of robust, large-scale clinical trials showing that supplementation beyond recommended dietary allowances enhances energy or combats fatigue in the general population. Thus, while the scientific basis for B5’s involvement in energy metabolism is strong, the evidence for its use as a supplement to increase energy in non-deficient individuals is weak.

In summary, vitamin B5 is critical for energy metabolism, but supplemental use to treat or support energy in the absence of deficiency is not strongly supported by clinical evidence.

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