Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Magnesium ascorbate is a compound that combines magnesium and vitamin C (ascorbic acid). Both magnesium and vitamin C have roles in normal energy metabolism, but the evidence supporting magnesium ascorbate specifically for treating or supporting energy levels (i.e., combating fatigue or lack of energy) is limited. Magnesium is a cofactor in many enzymatic reactions involved in energy production, particularly those generating ATP, the cellular energy currency. Magnesium deficiency can contribute to fatigue, and supplementation can improve energy in deficient individuals. Similarly, vitamin C is involved in reducing oxidative stress and is required for carnitine synthesis, a molecule important in energy production from fats. However, clinical trials directly investigating magnesium ascorbate for increasing energy in people without clear deficiencies are scarce. The evidence base for using magnesium ascorbate specifically for supporting energy is therefore modest and extrapolated mainly from the known roles of its component nutrients. There is no robust evidence that supplementation with magnesium ascorbate significantly boosts energy in healthy individuals. Most support for its use comes from its general nutritional benefits rather than targeted clinical studies. Thus, the scientific evidence is limited but present, justifying a moderate evidence rating.

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