Evidence supporting the use of: Citrulline aspartate
For the health condition: Energy (lack of)
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Citrulline aspartate is primarily supported by scientific evidence for its use in addressing fatigue and enhancing energy, especially in contexts of physical performance. The compound is a combination of the amino acid citrulline and aspartic acid. Multiple clinical studies, especially from the 1980s and onward, have investigated its effects on both central (mental) and peripheral (muscular) fatigue. Research indicates that citrulline aspartate can enhance the removal of ammonia (a byproduct of exercise that contributes to fatigue) and support the urea cycle, potentially reducing feelings of tiredness during physical activity. Some double-blind, placebo-controlled trials have demonstrated improvements in endurance and reduction in the perception of fatigue in athletes and individuals undergoing strenuous exercise. However, while the evidence is promising, it is not uniformly robust or large-scale, and most of the studies have been performed on exercise-induced fatigue rather than fatigue from chronic illnesses or general tiredness. There is also some evidence that citrulline aspartate may improve aerobic performance by enhancing ATP production and reducing muscle soreness. Overall, while citrulline aspartate has a scientific basis for supporting energy levels, primarily in athletic or high-exertion settings, more research is needed to fully confirm its benefits and to establish optimal dosing and safety in broader populations.
Other ingredients used for Energy (lack of)
7-Keto-DHEAacai berry
acetyl l-carnitine
adenosine 5-triphosphate disodium (ATP)
alpha d-ribofuranose
alpha-ketoglutarate (AKG)
amino acids
amylopectin
ashwagandha
aspartic acid
beta-alanine
biotin
black pepper
bасора
caffeine
capsaicinoids
coconut milk
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
eleuthero
folate
fructose
ginseng
greens blend (proprietary)
guarana
guayusa
l-alanyl-l-glutamine
l-carnitine
l-glutamine
l-glycine
l-leucine
l-tyrosine
maca
magnesium
malic acid
maltodextrin
medium chain triglycerides (MCT)
microbial enzymes (proprietary)
milk
Acetyl-L-Tyrosine
nettle
pantothenic acid (vitamin B5)
pollen
protein
pyrroloquinoline disodium salt
rhodiola
rosemary
sage
shiitake mushroom
black ginger
sphaeranthus indicus
spirulina
succinic acid
tongkat ali
almond fruit
vegetable blend (proprietary)
velvet bean
vitamin B
vitamin B12
vitamin B6
whey protein
zinc
suma
jiaogulan
alpinia galangal
commiphora
bee pollen
lemongrass
siler root
cistanche
sweet flag
electrolytes blend (proprietary)
trace minerals
yerba mate
wheat germ
algae
1,3,7-Trimethylpurine-2,6-dione
Aralia
akebia
Alpha polylactate
Antler
Agastache
Arginine Creatine
Ardisia
Arginine malate
Anamu
Areca
adenosine triphosphate (ATP)
Algal protein
Amor seco
Arginine silicate
Atractylone
Animal protein
Beta Phenethylalamine
Blackthorn
Beta-hydroxybutyrate
Beef liver
Bovine Protein
berry
Ba Ji Tian
Borassus Palm
Borassus aethiopum
banana
Baobab
Borneol
Chia seed
Coconut
Cinnamomum
Coenzyme A
coconut oil
Codonopsis
Cynomorium
Catecholamine
Chlorophytum
Chuchuhuasi
Curcumen
Coca
Chicken
cola nut
Dendrobium
Deer Root
Deer Velvet
Dragonhead
Dextrates
D-Ribose
Dextrose
Eurycomanone
Erodium cicutarium
Egg
Elk antler
Eurycoma Longifolia
Elthyl-Alpha-Guanido-Methyl-Ethanoate
Ecdysterone
Ephedrine
Egg protein
Gamma-Butyrobetaine
GMS-ribose
glucose
Garden Cress
Ketone Salts
Milk Protein
peanut
Shellfish
Wheat
Other health conditions supported by Citrulline aspartate
Athletic and Exercise AidsBody Building
Cardiovascular Disease
Circulation (poor)
Energy (lack of)
Fatigue
Muscle Tone (lack of)
