Chinese Goldthread (Coptis chinensis), also known as Huang Lian, is a traditional herb used in Chinese medicine primarily for its bitter and cooling properties. Historically, it has been applied to clear heat, dry dampness, and address conditions such as digestive disturbances, infections, and inflammation. In classical Chinese medicine, "lack of energy" or fatigue is often associated with imbalances such as damp-heat or deficiency syndromes. While Goldthread is not one of the primary herbs directly used to "tonify Qi" (the traditional concept roughly corresponding to energy), it may be included in formulas when fatigue is believed to be caused by underlying heat or dampness that obstructs the body's energy flow.

There is limited scientific evidence to support the use of Chinese Goldthread for general fatigue or lack of energy. Most research focuses on its antimicrobial, anti-inflammatory, and antioxidant properties, largely attributed to its primary active component, berberine. Some studies suggest berberine may improve metabolic function, which could theoretically influence energy levels, but these effects are not well-established for treating fatigue specifically. Overall, while Goldthread has a long history of use in traditional settings for conditions that can be associated with fatigue, it is not a core herb for directly boosting energy, and scientific evidence for this application is minimal.