Evidence supporting the use of: Capsaicinoids
For the health condition: Energy (lack of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Capsaicinoids, the active compounds found in chili peppers, have been studied for their potential effects on metabolism and energy expenditure. Some scientific evidence suggests that capsaicinoids can modestly increase energy expenditure and fat oxidation, primarily through thermogenic effects—raising body temperature and stimulating the sympathetic nervous system. Several randomized controlled trials and meta-analyses have demonstrated that capsaicinoid supplementation can lead to a small but statistically significant increase in resting metabolic rate and fat burning, which may contribute to a subjective feeling of increased energy.

However, the evidence for capsaicinoids directly treating or significantly improving subjective feelings of "energy" (i.e., combating fatigue or boosting alertness) is limited. Most studies focus on metabolic parameters, such as calorie burn and fat oxidation, rather than direct measures of energy levels or fatigue. The stimulatory effects, if present, are mild compared to substances like caffeine. Traditional medical systems do not commonly use capsaicinoid-rich plants specifically for energy enhancement, but rather for digestive or circulatory purposes.

In summary, while there is some scientific basis for capsaicinoids supporting increased metabolic energy expenditure, the evidence for their use in treating general lack of energy or fatigue is weak, warranting a score of 2 out of 5. Most claims about capsaicinoids boosting energy are extrapolated from their metabolic effects, not from robust clinical trials measuring subjective energy or fatigue outcomes.

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7-Keto-DHEA
Acai berry
Acetyl L-carnitine
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adenosine 5-triphosphate disodium (ATP)
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alpha-ketoglutarate (AKG)
alpinia galangal
amino acids
Amor seco
anamu
animal protein
antler
Aralia
Ardisia
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arginine creatine
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ashwagandha
aspartic acid
atractylone
ba ji tian
banana
baobab
bee pollen
Beef liver
berry
beta phenethylalamine
beta-alanine
beta-hydroxybutyrate
biotin
black ginger
black pepper
blackthorn
Borassus aethiopum
borassus palm
borneol
bovine protein
bасора
caffeine
capsaicinoids
catecholamine
chia seed
Chlorophytum
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cistanche
coca
coconut
coconut milk
coconut oil
Codonopsis
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coenzyme Q10 (CoQ10)
coffee fruit
cola nut
commiphora
cordyceps
creatine monohydrate
curcumen
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D-Ribose
deer root
deer velvet
Dendrobium
dextrates
dextrose
dragonhead
ecdysterone
egg
Egg protein
electrolytes blend (proprietary)
eleuthero
elk antler
ephedrine
Erodium cicutarium
Ethyl-Alpha-Guanido-Methyl-Ethanoate
Eurycoma Longifolia
eurycomanone
folate
fungus
gamma-butyrobetaine
garden cress
ginseng
glucose
GMS-ribose
greens blend (proprietary)
guarana
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guayusa
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Higenamine
Ilex
jiaogulan
jungli-bean
ketone salts
ketosterones
kola nut
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l-carnitine
L-glutamine
L-glycine
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l-tyrosine
lemongrass
lipids
maca
macaenes
macamides
magnesium
malic acid
maral root
medium chain triglycerides (MCT)
Methylliberine
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Milk
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ornithine L-aspartic acid
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oxaloacetic acid
pantothenic acid (vitamin B5)
paraxanthine
peanut
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