Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-Alanyl-Glutamine is a dipeptide composed of the amino acids L-alanine and L-glutamine. It is used in some sports supplements with the aim of supporting hydration and endurance, particularly in endurance athletes. The scientific basis for its use centers on the stability and bioavailability of glutamine; L-Alanyl-Glutamine is more stable in solution and may enhance glutamine delivery to muscle cells when compared to free glutamine. Several small-scale studies have investigated its effects on exercise performance. For example, research indicates that supplementation may help maintain hydration status by enhancing fluid and electrolyte absorption in the intestines, potentially delaying fatigue during prolonged exercise. Some studies have also observed improvements in time-to-exhaustion or subjective fatigue perception in athletes supplementing with L-Alanyl-Glutamine versus placebo, though effects are generally modest and not universally observed. Nevertheless, the evidence base remains limited, with few well-powered, long-term studies directly linking L-Alanyl-Glutamine supplementation to significant improvements in endurance performance. Most findings suggest possible benefits for hydration and recovery, rather than robust, primary enhancements in endurance capacity. In summary, while there is a plausible mechanism and some supportive data, the scientific evidence is moderate and not definitive.

More about L-Alanyl-Glutamine
More about Endurance (lack of)

Other ingredients used for Endurance (lack of)

Other health conditions supported by L-Alanyl-Glutamine

Products containing L-Alanyl-Glutamine