Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Pluchea, particularly Pluchea indica and Pluchea odorata, has a history of use in traditional medicine systems in Asia and the Americas. Traditional healers have used Pluchea species for a variety of respiratory ailments, including coughs, colds, asthma, and sometimes more serious lung conditions. The rationale for its use in emphysema is primarily based on these broader applications for respiratory complaints rather than direct, specific evidence for emphysema itself. There are anecdotal reports and traditional records that suggest Pluchea may act as an expectorant or anti-inflammatory agent, which could theoretically offer symptomatic relief for individuals with chronic obstructive pulmonary diseases (COPD), a category that includes emphysema. However, scientific research directly evaluating the efficacy or safety of Pluchea in the treatment of emphysema is lacking. No clinical trials or robust preclinical studies have established a mechanism or demonstrated clear benefit in emphysema models. The plant does contain compounds with anti-inflammatory and antioxidant effects, which are relevant to emphysema pathology, but this connection remains speculative when applied to human disease. In summary, the use of Pluchea for emphysema is rooted in traditional medicine and general respiratory support, not in scientific validation or targeted clinical evidence.

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