Relationship: Emotional Sensitivity and vitamin B6

Evidence supporting the use of: Vitamin B6
For the health condition: Emotional Sensitivity

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Source of validity: Scientific
Rating (out of 5): 2

Vitamin B6 (pyridoxine) has been investigated for its role in supporting emotional health, particularly in people experiencing premenstrual syndrome (PMS), mood swings, and heightened emotional sensitivity. Its involvement is rooted in its function as a coenzyme in the synthesis of neurotransmitters such as serotonin, dopamine, and gamma-aminobutyric acid (GABA), all of which play key roles in mood regulation.

Several small clinical trials and observational studies have shown that vitamin B6 supplementation can help reduce symptoms of PMS, including irritability, moodiness, and emotional lability. For example, a 2017 meta-analysis found that vitamin B6 supplementation had a modest effect in reducing overall PMS symptoms, particularly mood-related symptoms, compared to placebo. The proposed mechanism is that vitamin B6 helps optimize neurotransmitter production, potentially stabilizing mood and emotional responses.

However, the evidence is mixed and often limited by small sample sizes, variable dosages, and short study durations. There is less robust evidence for the use of vitamin B6 specifically for emotional sensitivity outside of PMS or clinical depression. While some studies suggest benefit in reducing symptoms of depression or anxiety, these effects are generally small and inconsistent.

In summary, while there is some scientific rationale and limited clinical evidence supporting the use of vitamin B6 for mood regulation and emotional sensitivity, especially in the context of PMS, the strength of evidence is modest. Further, larger-scale and rigorous studies are needed to confirm its efficacy for emotional sensitivity more broadly.

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Evidence supporting the use of: Vitamin B6
For the health condition: Emotional Sensitivity

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Evidence supporting the use of: Vitamin B6For the health condition: Emotional Sensitivity

Table of Contents

Synopsis

Other ingredients used for Emotional Sensitivity

Other health conditions supported by vitamin B6

Products containing vitamin B6

Evidence supporting the use of: Vitamin B6
For the health condition: Emotional Sensitivity