Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Thaumatococcus daniellii, commonly known as the African serendipity berry, is a plant with a long history of ethnomedicinal use in West and Central Africa. Among the various traditional uses reported by local communities, the application of leaves or extracts for the management of edema (swelling caused by fluid retention) has been documented in some ethnobotanical surveys. The rationale is primarily based on folk knowledge, where the leaves are believed to possess diuretic or anti-inflammatory properties, leading to the reduction of swelling.

However, scientific validation for this specific use remains limited. While a few laboratory studies have investigated the general pharmacological effects of T. daniellii extracts—such as antioxidant, anti-inflammatory, and antimicrobial activities—direct studies on its efficacy for edema in humans or animal models are lacking. No clinical trials or robust preclinical studies have validated its diuretic potential or effectiveness in treating edema. Thus, the support for using Thaumatococcus daniellii for edema is grounded primarily in traditional usage rather than in well-established scientific evidence. Researchers recommend further studies to clarify its potential mechanism and safety profile for this indication.

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