Evidence supporting the use of: Rutin
For the health condition: Edema

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rutin, a natural flavonoid found in various plants such as buckwheat, citrus fruits, and apples, has been studied for its potential benefits in managing edema, particularly chronic venous insufficiency (CVI) and related vascular conditions. The scientific rationale for its use lies in rutin's ability to strengthen capillaries, reduce capillary permeability, and exert anti-inflammatory and antioxidant effects. Several clinical studies and reviews have investigated flavonoids, including rutin and its closely related compound troxerutin, for their impact on venous tone and microcirculatory function. Some randomized trials and meta-analyses suggest a modest benefit in decreasing leg edema and improving symptoms in patients with CVI, although the quality and size of studies are variable. The European Medicines Agency recognizes "bioflavonoids" (a class including rutin) as traditional herbal medicinal products for relief of symptoms of CVI, but also notes that high-quality clinical evidence is limited. While rutin is not a first-line or universally accepted therapy for edema, particularly where edema is caused by heart, kidney, or liver disease, it has some scientific support for symptom relief in venous-related swelling. The evidence base is not robust enough to warrant a high rating, but its use is more than just tradition, with some mechanistic and clinical data supporting its role.

More about rutin
More about Edema

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burdock
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citrus bioflavonoids
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onion
hawthorn
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jujube
lemon
lophatherum leaf
lovage
mannitol
moringa
mustard seed
nettle
papain
parsley
pear
pine bark
pineapple
potassium
protease
pumpkin
quercetin
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scrophularia root
serratiopeptidase
specialized pro-resolving mediators (SPMs)
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trypsin
seaweed
watermelon
sarsaparilla
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tangerine
xanthium (cockleburs)
atractylodes
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alpinia galangal
punarnava
commiphora
rubia cordifolia
swertia
lingusticum wallichii
goldenrod
prickly ash
lemongrass
silk tree
juniper berries
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siler root
amber
dioscorea
dodder
sweet flag
hyacinth bean
morinda
cornsilk
buchu
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couch grass
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queen of the meadow
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