Polygonatum species, commonly known as Solomon's Seal, have a long history of use in traditional medicine, particularly within Chinese, Korean, and other East Asian herbal systems. In Traditional Chinese Medicine (TCM), Polygonatum (often Polygonatum sibiricum or Polygonatum odoratum) is known as "Yu Zhu" or "Huang Jing" and is valued for its purported abilities to nourish yin, moisten dryness, and tonify the body. Edema, characterized by the accumulation of fluid in tissues, is sometimes attributed to imbalances in bodily fluids or deficiencies in TCM theory, and herbs that support kidney function or promote fluid metabolism are often used.

Historical texts and traditional pharmacopeias occasionally mention Polygonatum as an adjunctive herb in formulas aimed at alleviating mild edema, especially when associated with underlying weakness or yin deficiency. However, its use is more commonly centered around nourishing and moistening rather than direct diuretic action. Scientific studies examining Polygonatum's efficacy for edema are very limited, and most available research focuses on its antioxidant, anti-inflammatory, and immunomodulatory properties rather than effects on fluid retention or renal function. Some animal studies suggest mild diuretic activity, but these are preliminary and not widely replicated.

In summary, while Polygonatum is sometimes used in traditional medicine for conditions related to fluid balance, there is minimal scientific evidence to specifically support its use for edema. The justification lies primarily in tradition rather than rigorous clinical validation.