Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Pine bark extract, particularly from the French maritime pine (Pinus pinaster) and sold under the trademarked name Pycnogenol®, has been studied for its potential benefits in reducing edema (swelling), especially in cases of chronic venous insufficiency and after certain surgeries or injuries. The scientific support stems from several small clinical trials and reviews.

The proposed mechanism involves pine bark’s rich content of procyanidins and other polyphenols, which have antioxidant and anti-inflammatory properties. These compounds are thought to strengthen capillary walls, reduce capillary permeability, and improve microcirculation, thereby decreasing fluid leakage into tissues – a core feature of edema.

Several randomized, placebo-controlled studies (for example, Cesarone et al., 2006; Belcaro et al., 2011) have found that Pycnogenol® supplementation can reduce leg swelling and improve symptoms in people with chronic venous insufficiency, a common cause of lower limb edema. Some evidence also suggests benefits in reducing postoperative edema. However, the studies tend to be small, sometimes industry-funded, and longer-term safety and efficacy data are limited.

Overall, while there is a scientific rationale and some clinical evidence supporting pine bark extract's use for edema, the quality and size of available studies warrant a moderate evidence rating. More large-scale, independent trials are needed to confirm these findings and establish standardized dosing protocols.

More about pine bark
More about Edema

Other ingredients used for Edema

Other health conditions supported by pine bark

Products containing pine bark

Nature's Sunshine High Potency Grapine
Nature's Sunshine Grapine With Protectors (SynerPro)