Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Citrus nobilis, commonly known as mandarin orange, has a history of use in traditional medicine systems, particularly in East Asia. In Traditional Chinese Medicine (TCM), the dried peel of Citrus nobilis (often referred to as "Chen Pi" or "Jupi") is used in various herbal formulations. It is believed to regulate Qi (energy), resolve phlegm, and promote digestion. While not a primary remedy for edema, some traditional formulations include Chen Pi for its supposed ability to support fluid metabolism and reduce dampness, which in TCM theory can relate to conditions involving swelling and water retention (edema).

However, there is limited direct scientific evidence supporting the efficacy of Citrus nobilis or its extracts in the treatment of edema as defined by modern medicine (i.e., swelling caused by fluid accumulation). Some in vitro and animal studies have suggested that citrus peel extracts may have mild diuretic or anti-inflammatory properties, but these findings are preliminary and not specific to Citrus nobilis for edema. The use of Citrus nobilis for edema is thus primarily justified by tradition, with a low evidence rating due to the absence of robust clinical data.

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