Celrodendrum indicum (more commonly spelled as Clerodendrum indicum) has a history of use in traditional medicine systems, particularly in Ayurveda and traditional folk medicine in India and Southeast Asia. The plant is valued for its purported diuretic, anti-inflammatory, and detoxifying properties, which are relevant to the management of edema—a condition characterized by excess fluid accumulation in tissues. Traditional practitioners have used preparations made from the roots and leaves of Clerodendrum indicum to reduce swelling and fluid retention in various ailments.

The scientific evidence supporting its use for edema is limited but not entirely absent. Some preclinical studies have reported that extracts of Clerodendrum indicum possess diuretic activity in animal models, which could mechanistically justify its traditional use for edema. Additionally, anti-inflammatory and antioxidant properties documented in laboratory models may provide ancillary benefits in conditions involving fluid buildup and tissue inflammation. However, these studies are preliminary, often lacking standardized extracts, clinical data, or robust human trials specifically targeting edema.

In summary, the use of Clerodendrum indicum for edema is primarily supported by traditional practices, with some early scientific indications of diuretic and anti-inflammatory effects. High-quality clinical trials are lacking, so while the traditional use is well-documented, scientific validation remains modest at this time.