Evidence supporting the use of: Atractylodes
For the health condition: Edema

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Atractylodes, particularly Atractylodes macrocephala, has a long history of use in Traditional Chinese Medicine (TCM) for addressing edema (fluid retention and swelling). In TCM, this herb is considered to strengthen the Spleen and promote the transformation and transportation of fluids, which is believed to help resolve dampness and reduce swelling. Classic texts, such as the Shennong Bencao Jing and Bencao Gangmu, describe atractylodes as beneficial for symptoms associated with water retention, including edema, especially when it is attributed to Spleen Qi deficiency.

Scientific evidence supporting the use of atractylodes for edema is limited. Some modern pharmacological studies indicate that Atractylodes macrocephala has diuretic effects in animal models, which may partially explain its historical application for fluid retention. These studies suggest that extracts of the plant can increase urine output and promote fluid excretion. However, high-quality human clinical trials are lacking, and the mechanisms underlying these effects remain unclear. The majority of available evidence remains anecdotal or based on traditional use rather than rigorous scientific validation.

In summary, the use of atractylodes for edema is primarily justified by traditional medical systems like TCM, with limited preliminary scientific evidence suggesting possible diuretic properties. More robust clinical research is needed to confirm its efficacy and safety for this indication in humans.

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