Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E, particularly in the form of vitamin E acetate, has some scientific support for its use in the management of eczema, though the evidence is limited and not robust. Vitamin E is an antioxidant and has anti-inflammatory properties, which theoretically could help with the oxidative stress and inflammation associated with eczema (atopic dermatitis). Several small-scale studies and clinical trials have explored oral and topical vitamin E supplementation for eczema. For example, a double-blind, placebo-controlled study published in 2015 found that oral vitamin E supplementation (400 IU/day) for eight months led to a significant reduction in eczema severity compared to placebo. Some topical formulations containing vitamin E are also marketed for their skin-soothing properties, though clinical evidence for topical efficacy is less consistent.

Despite these findings, the overall quality and quantity of evidence are modest. Systematic reviews and dermatology guidelines generally do not recommend vitamin E as a first-line therapy for eczema due to insufficient large, well-controlled studies. However, vitamin E is occasionally used as an adjunct therapy, especially by individuals seeking complementary or alternative approaches. The use of vitamin E for eczema is therefore justified by some scientific evidence, albeit weak, rather than by longstanding tradition or complete lack of evidence.

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