Evidence supporting the use of: Vitex negundo
For the health condition: Dysmenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitex negundo, commonly known as the Chinese chaste tree or Nirgundi, has a long history of use in traditional medicine systems such as Ayurveda, Siddha, and Unani. In these traditions, it is used for a variety of gynecological conditions, including dysmenorrhea (painful menstruation). The leaves, roots, and seeds are utilized in various forms such as decoctions, oils, or powders. Ancient texts and ethnobotanical surveys cite its analgesic, anti-inflammatory, and antispasmodic properties, which are believed to help alleviate menstrual pain and related symptoms.

However, while there are preclinical studies (in vitro and animal research) suggesting anti-inflammatory and analgesic effects of Vitex negundo extracts, direct scientific evidence from human clinical trials specifically investigating its efficacy in treating dysmenorrhea is lacking. Most of the support for its use comes from traditional knowledge, case reports, and anecdotal evidence rather than robust clinical validation. Some phytochemical studies have identified flavonoids and iridoid glycosides in Vitex negundo, which might contribute to its purported effects, but these findings have not yet been translated into well-designed clinical studies for dysmenorrhea.

In summary, the use of Vitex negundo for dysmenorrhea is primarily based on traditional practice, with limited scientific evidence currently available to support its effectiveness for this specific condition.

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