Evidence supporting the use of: Trichosanthes
For the health condition: Dysmenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Trichosanthes, a genus that includes Trichosanthes kirilowii and Trichosanthes cucumerina, has a long history of use in traditional Chinese medicine (TCM) and other Asian medical systems. In TCM, various parts of the plant (such as the root, fruit, and seeds) are used to "clear heat," "transform phlegm," and promote the movement of "qi and blood." Dysmenorrhea (painful menstruation) is often attributed in TCM to stagnation of blood or qi, and Trichosanthes is sometimes included in herbal formulas intended to address these imbalances and relieve menstrual pain. However, the use for dysmenorrhea is not prominent or primary; more commonly used herbs for menstrual pain in TCM include Angelica sinensis (dong quai) and Paeonia lactiflora (white peony).

Scientific studies specifically evaluating Trichosanthes for dysmenorrhea are extremely limited. There is some laboratory and animal research indicating that extracts from this genus may have anti-inflammatory, analgesic, and smooth muscle relaxant properties, which could theoretically be beneficial for menstrual pain. However, clinical trials in humans for this indication are lacking. Thus, while there is a traditional rationale for its inclusion in some herbal formulas for dysmenorrhea, strong scientific validation is not present, and the evidence is best described as traditional with limited support (rating: 2).

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