Evidence supporting the use of: Nutmeg & Mace
For the health condition: Dysmenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Nutmeg (Myristica fragrans) and its aril, mace, have a long history of use in traditional medicine for various ailments, including menstrual disorders such as dysmenorrhea (painful menstruation). In Ayurvedic and Unani medicine, both nutmeg and mace are considered to have warming, analgesic, and antispasmodic properties, and are sometimes included in formulations intended to ease menstrual cramps and discomfort. The traditional rationale is based on their reputed ability to promote circulation, relax smooth muscle, and reduce pain.

However, scientific evidence to substantiate these uses is limited. There are a few animal studies suggesting that nutmeg extracts may exhibit analgesic and anti-inflammatory effects, which could theoretically benefit dysmenorrhea. For example, some preclinical research has observed reduced pain responses and inflammation in rodent models following administration of nutmeg extracts. Nonetheless, robust clinical trials in humans specifically evaluating the efficacy and safety of nutmeg or mace for dysmenorrhea are lacking.

In summary, the use of nutmeg and mace for dysmenorrhea is primarily justified by traditional medicine systems and historical practices, with limited preclinical support but insufficient scientific validation in human studies. Caution is also warranted due to potential toxicity of nutmeg in high doses.

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