Evidence supporting the use of: Hedyotis diffusa
For the health condition: Dysmenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Hedyotis diffusa (commonly known as Oldenlandia diffusa or Bai Hua She She Cao) is primarily used in traditional Chinese medicine (TCM) for a range of conditions, most notably as an anti-inflammatory and anticancer herb. Its use for dysmenorrhea (menstrual pain) is based on its traditional application for "clearing heat" and "detoxifying" the body, as well as promoting blood circulation and reducing inflammation. In TCM, dysmenorrhea is sometimes attributed to "stagnation of blood," and herbs like Hedyotis diffusa are occasionally included in multi-herb formulas intended to alleviate this stagnation.

However, while there is substantial documentation of its traditional uses, direct scientific evidence supporting Hedyotis diffusa for dysmenorrhea is limited. Most pharmacological studies on Hedyotis diffusa focus on its anticancer, antibacterial, and anti-inflammatory effects, rather than gynecological or menstrual conditions. There are a few preclinical studies suggesting anti-inflammatory actions that could, in theory, benefit menstrual pain, but no high-quality clinical trials specifically address its efficacy for dysmenorrhea. Therefore, its use for this condition is primarily justified by tradition rather than robust scientific validation.

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