Evidence supporting the use of: Calotropis gigantea
For the health condition: Dysmenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Calotropis gigantea, commonly known as Crown Flower or Giant Milkweed, has been used in traditional medicine systems, particularly in Ayurveda and folk medicine in South Asia, for a variety of ailments including dysmenorrhea (painful menstruation). Historical texts and ethnobotanical surveys document its use as an emmenagogue (an agent that stimulates menstrual flow) and in alleviating menstrual cramps. Various parts of the plant, especially the roots and leaves, have been prepared as decoctions or poultices for women experiencing menstrual pain.

Regarding scientific validation, there is limited direct research evaluating the efficacy of Calotropis gigantea specifically for dysmenorrhea. Some laboratory studies have demonstrated that extracts from the plant exhibit anti-inflammatory, analgesic, and antispasmodic properties in animal models or in vitro, all of which could theoretically contribute to relief of menstrual pain. However, these findings are preliminary and not specific to dysmenorrhea in humans. No high-quality clinical trials have been published to confirm its effectiveness for this use.

In summary, the use of Calotropis gigantea for dysmenorrhea is primarily justified by traditional knowledge, with some supportive but indirect pharmacological evidence. The overall strength of evidence is low (rated 2/5) due to the lack of clinical studies directly linking the plant to relief of menstrual pain in humans.

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Products containing Calotropis gigantea

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