Evidence supporting the use of: Alpha-linolenic acid (ALA)
For the health condition: Dysmenorrhea
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Alpha-linolenic acid (ALA) has some scientific support for its use in the management of dysmenorrhea (painful menstruation), though the evidence is not robust. ALA is an omega-3 fatty acid found in plant sources such as flaxseed, chia seeds, and walnuts. Omega-3 fatty acids are thought to have anti-inflammatory properties that may help reduce menstrual pain, which is believed to be partly due to the production of pro-inflammatory prostaglandins in the uterus. A limited number of clinical studies have investigated the effects of omega-3 fatty acids, including ALA, on dysmenorrhea. Most research has focused on eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are longer-chain omega-3s derived from ALA. However, a few studies suggest that increased intake of ALA-rich foods or supplements may help decrease the severity of menstrual pain. For example, a randomized controlled trial published in Obstetrics & Gynecology Science (2018) found that flaxseed supplementation (a rich source of ALA) led to a significant reduction in menstrual pain intensity compared to placebo. The mechanism is thought to involve the modulation of prostaglandin synthesis, reducing uterine contractions and inflammation. Overall, while there is some preliminary scientific evidence suggesting a benefit of ALA in dysmenorrhea, more high-quality, large-scale studies are needed. The evidence is currently rated as weak to moderate (2/5), and ALA should not be considered a primary or sole treatment for dysmenorrhea but may be considered as a complementary approach.
More about alpha-linolenic acid (ALA)
More about Dysmenorrhea
Other ingredients used for Dysmenorrhea
AbutaAchyranthes
Actaea spicata
Aerva lanata
Agnuside
Agrimonia pilosa
Albizia
Alchemilla
Aletris
alpha-linolenic acid (ALA)
ambergris
anamu
Anemone
Angelica
anise
Anserina
Arisaema
Ashoka
avens
bethroot
black cohosh
Blepharis
blue cohosh
Boerhavia diffusa
Boswellia
calcium
Calendula
Calotropis gigantea
chamomile
chaste tree
cohosh
Corydalis
Cyathula
Didymocarpus
dioscorea
dong quai
dong quai root
EPA (eicosapentaenoic acid)
Erythropalum scandens
Euphorbia
Eupolyphaga sinensis
evening primrose oil
fennel
fish oil
gastrodia
ginger
Labisia pumila
Lady's Mantle
Lophira lanceolata
magnesium
Mezoneuron benthamianum
Montanoa tomentosa
Motherwort
omega-3 fatty acids
parsley
passionflower
Pennyroyal
peony
Peppermint
phytocannabinoids
Phytoestrogens
poppy
Pulsatilla
rue
Semecarpus anacardium
shepherd's purse
Trichosanthes
Viburnum
vitamin B6
vitamin E
Vitex Agnus-Castus
Wild yam
Other health conditions supported by alpha-linolenic acid (ALA)
Aging (prevention)Alzheimer's Disease
Arteriosclerosis
Arthritis
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Depression
Eczema
Fat Metabolism (poor)
Fatty Liver Disease
Hypertension
Inflammation
Inflammatory Bowel Disorders
Metabolic Syndrome
Psoriasis
Rheumatoid Arthritis
Skin (dry and/or flaky)
Triglycerides (high)
Diabetes
Dementia
Migraine
Dysmenorrhea
