Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Coin-leaf desmodium (Desmodium gangeticum) has a long history of use in traditional medicine systems, particularly Ayurveda and folk medicine across South and Southeast Asia. In these systems, the plant is often employed for its reputed anti-diarrheal, anti-dysenteric, and anti-inflammatory properties. Traditional healers have used decoctions or extracts from the roots and leaves to manage cases of dysentery, diarrhea, and other gastrointestinal disturbances. The rationale is generally based on broad observations of symptom relief in communities rather than formal scientific investigation.

However, scientific validation of these uses is limited. Some in vitro and animal studies have indicated that extracts of Desmodium gangeticum possess antimicrobial and anti-inflammatory activities, which could theoretically help combat the pathogens and inflammation involved in dysentery. For example, studies have shown inhibition of certain bacteria associated with gastrointestinal infections. Nevertheless, clinical studies in humans are lacking, and no robust randomized controlled trials have confirmed its efficacy or safety specifically for dysentery. Thus, while traditional use is well-documented, scientific evidence supporting its effectiveness for this condition remains preliminary and insufficient for clinical recommendations.

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