Evidence supporting the use of: Agrimonia pilosa
For the health condition: Dysentery

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Agrimonia pilosa has a long history of use in traditional Chinese medicine (TCM) and other East Asian medical systems as a treatment for dysentery and various gastrointestinal disorders. Historical texts, such as the ancient Chinese Shennong Bencao Jing and later TCM materia medica, cite Agrimonia pilosa as an astringent herb used to stop bleeding and to treat conditions characterized by diarrhea with blood or mucus, commonly associated with dysentery. The plant is thought to act by "clearing heat," "detoxifying," and "astringing the intestines" in TCM theory.

While modern pharmacological studies have identified antimicrobial, anti-inflammatory, and astringent compounds in Agrimonia pilosa (such as agrimonin, flavonoids, and tannins), direct clinical evidence supporting its efficacy for dysentery in humans is lacking. Most studies are in vitro or animal-based, indicating potential antibacterial activity against pathogens that can cause dysentery, but human trials are absent or of low quality. Therefore, its use for dysentery is primarily justified by tradition, with some preliminary scientific rationale but insufficient clinical validation. The overall evidence rating is a 2, reflecting strong traditional but limited scientific support.

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