Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Aloe vera has a long history of traditional use for various gastrointestinal ailments, and recent scientific studies have begun to explore its efficacy in supporting or treating duodenal ulcers. The primary rationale for its use stems from its well-documented anti-inflammatory, antioxidant, and mucosal protective properties. Several in vitro and animal studies have demonstrated that aloe vera gel can reduce gastric acid secretion, promote mucous secretion, and facilitate healing of gastric and duodenal mucosa. For example, a 2004 study in rats found that aloe vera extract significantly accelerated the healing of induced gastric ulcers and reduced ulcer area, likely due to increased mucus production and antioxidant effects.

Human evidence, however, remains limited. Some small-scale clinical studies suggest potential benefits in reducing ulcer symptoms and promoting healing, but these studies often lack rigorous controls or have small sample sizes. Additionally, aloe vera polysaccharides are thought to enhance mucosal defense and inhibit pepsin activity, which can contribute to ulcer healing. Despite these promising findings, there are currently no large-scale randomized controlled trials that firmly establish aloe vera as an effective treatment for duodenal ulcers in humans. Thus, while preliminary scientific evidence exists to support its use, the overall quality and quantity of evidence remain modest, justifying a score of 2 on the evidence scale.

More about aloe vera
More about Duodenal Ulcers

Other ingredients used for Duodenal Ulcers

Other health conditions supported by aloe vera

Products containing aloe vera

Nature's Sunshine CleanStart Mild
Nature's Sunshine Aloe Vera (Freeze Dried)
Nature's Sunshine Aloe Vera Gel
Nature's Sunshine Aloe Vera Juice
Nature's Sunshine Aloe Vera Juice (Whole Leaf)
Nature's Sunshine Liquid Cleanse