Synopsis

Source of validity: Scientific
Rating (out of 5): 2

There is some scientific evidence supporting the use of prebiotics in managing diverticulitis, although the evidence is limited and primarily indirect. Prebiotics are non-digestible food ingredients that promote the growth of beneficial gut bacteria, such as Bifidobacteria and Lactobacilli. Since diverticulitis is associated with changes in the gut microbiota and inflammation of diverticula in the colon, strategies that improve gut flora balance are of interest.

A few small clinical studies and reviews suggest that prebiotics may help reduce inflammation and improve gut health, potentially lowering the risk of recurrent diverticulitis or alleviating symptoms during remission. For example, some trials have investigated fiber supplements (which act as prebiotics) and observed improvements in bowel regularity and reductions in some symptoms. However, most research focuses on dietary fiber in general, rather than specific prebiotic compounds.

There is not enough high-quality, direct evidence from large randomized controlled trials specifically examining prebiotic supplementation in acute diverticulitis. Current clinical guidelines do not recommend prebiotics as a primary treatment for active diverticulitis but do suggest a high-fiber diet during remission, which may include prebiotic-rich foods. Therefore, while the rationale for prebiotic use is scientifically plausible and supported by some preliminary data, the overall evidence remains modest.

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