Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Aloe polysaccharides, primarily derived from Aloe vera gel, have a longstanding history of traditional use for soothing skin irritation, including minor burns, abrasions, and rashes. In the context of diaper rash, the application of Aloe-based preparations is largely justified by this tradition of use. Historical records and ethnobotanical sources describe the topical application of Aloe gel for skin inflammation, which has led to its inclusion in various over-the-counter diaper rash creams and ointments. The mucilaginous polysaccharides present in Aloe are thought to provide a cooling, moisturizing barrier on the skin, which may help reduce irritation and promote comfort.

However, while several in vitro and animal studies suggest that Aloe polysaccharides have anti-inflammatory, wound-healing, and moisturizing properties, high-quality clinical evidence specifically supporting their effectiveness for diaper rash in infants is limited. A few small studies and anecdotal reports indicate potential benefit, but systematic reviews note the lack of robust, well-controlled trials in this context. The available scientific evidence is thus insufficient to strongly validate its use for diaper rash beyond what tradition suggests. In summary, Aloe polysaccharide's use in diaper rash is mainly founded on traditional practice, with only low to moderate scientific support.

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