Evidence supporting the use of: Vitamin E (delta-tocopherol)
For the health condition: Diabetic Retinopathy
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin E, including its delta-tocopherol form, has been investigated as a potential therapeutic agent for diabetic retinopathy due to its antioxidant properties. Diabetic retinopathy is characterized by microvascular damage and increased oxidative stress within the retina. Vitamin E is known to scavenge reactive oxygen species, which theoretically could help protect retinal cells from the oxidative damage observed in this condition.
However, while some small-scale studies and animal experiments suggest benefits of Vitamin E supplementation in reducing oxidative stress and improving certain retinal parameters, clinical evidence in humans is limited and inconsistent. Most of the research focuses on alpha-tocopherol, the most common form of Vitamin E in supplements, rather than delta-tocopherol specifically. A few human trials have reported minor improvements in retinal blood flow or vascular function with Vitamin E supplementation, but these studies often have small sample sizes, short durations, and sometimes lack rigorous controls.
Major clinical guidelines do not currently recommend Vitamin E (including delta-tocopherol) as a standard treatment for diabetic retinopathy. Overall, while there is scientific rationale and preliminary evidence suggesting a possible benefit, the quality and quantity of human data supporting the use of Vitamin E (especially delta-tocopherol) for diabetic retinopathy is low. Well-powered, long-term clinical trials are needed to establish efficacy and safety.
More about Vitamin E (delta-tocopherol)
More about Diabetic Retinopathy
Other ingredients used for Diabetic Retinopathy
alpha-glycosyl isoquercitrinanthocyanins
astaxanthin
bilberry
black currant
blueberry
chlorella
chokeberry
turmeric
d-alpha tocopherol
flavonols
garlic bulb
ginger
grape
green tea
hesperidin
L-carnosine
lutein
lycopene
mixed carotenoids
pomegranate
quercetin
resveratrol
rutin
specialized pro-resolving mediators (SPMs)
spirulina
tocotrienols
vitamin C
vitamin D
vitamin E
Zinc
ferulic acid
polyphenols
AMP-activated protein kinase (AMPK)
apigenin
Aronia melanocarpa
alpha-lipoic acid
anthocyanidins
anthocyanosides
apocynin
astragalin
Boswellic Acid
benfotiamine
bioflavonoids
baicalin
beta-glucogallin
caffeic Acid
Carnosine
cyanidin
Curcuminoid
crocetin
delphinidin
dihydrolipoic acid
eicosapentaenoic acid
flavonoids
flavans
flavanols
ginkgo flavone glycoside
Glutathione
Hyperoside
Kaempferol
Oligomeric proanthocyanidins
Osthole
procyanidol
procyanidin
proanthocyanidins
Pycnogenol
Peptides
Salvianolic acid
Sulforaphane
Troxerutin
Verbascoside
Xanthophyll
Other health conditions supported by Vitamin E (delta-tocopherol)
Aging (prevention)Alzheimer's Disease
Dermatitis
Diabetic Retinopathy
Eczema
Free Radical Damage
Inflammation
Macular Degeneration