Evidence supporting the use of: Cyanidin
For the health condition: Diabetic Retinopathy
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Cyanidin is an anthocyanin, a type of flavonoid pigment found in various fruits and vegetables, such as berries and red cabbage. Some scientific evidence suggests that cyanidin and related anthocyanins may have beneficial effects in diabetic retinopathy, primarily due to their antioxidant and anti-inflammatory properties. Preclinical studies (animal and in vitro) have shown that cyanidin can reduce oxidative stress, inhibit vascular endothelial growth factor (VEGF) expression, and protect retinal cells from hyperglycemia-induced damage, all of which are relevant mechanisms in diabetic retinopathy. For example, studies in diabetic rodents have demonstrated that anthocyanin supplementation can reduce retinal damage and vascular leakage. However, human clinical data are limited. Few, if any, high-quality randomized controlled trials have evaluated cyanidin specifically for diabetic retinopathy in humans. Most human studies involve anthocyanin-rich extracts rather than isolated cyanidin, and improvements reported are often modest or secondary outcomes. In summary, while there is some scientific basis from laboratory and animal studies supporting the potential of cyanidin for diabetic retinopathy, the direct clinical evidence in humans is weak, resulting in a low-to-moderate (2/5) evidence rating.
Other ingredients used for Diabetic Retinopathy
alpha-glycosyl isoquercitrinanthocyanins
astaxanthin
bilberry
black currant
blueberry
chlorella
chokeberry
turmeric
d-alpha tocopherol
flavonols
garlic bulb
ginger
grape
green tea
hesperidin
l-carnosine
lutein
lycopene
mixed carotenoids
pomegranate
quercetin
resveratrol
rutin
specialized pro-resolving mediators (SPMs)
spirulina
tocotrienols
vitamin C
vitamin D
vitamin E
zinc
ferulic acid
polyphenols
AMP-activated protein kinase (AMPK)
Apigenin
Aronia melanocarpa
Alpha-Lipoic Acid
anthocyanidins
anthocyanosides
Apocynin
Astragalin
Boswellic Acid
Benfotiamine
Bioflavonoids
Baicalin
Beta-glucogallin
Caffeic Acid
Carnosine
Cyanidin
Curcuminoid
Crocetin
Delphinidin
Dihydrolipoic Acid
Eicosapentaenoic Acid
Other health conditions supported by Cyanidin
Alzheimer's DiseaseArthritis
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Diabetes
Diabetic Retinopathy
Inflammation
Macular Degeneration
Memory and Brain Function
Metabolic Syndrome
Osteoporosis
Rheumatoid Arthritis
Triglycerides (high)
Ulcers
Wounds and Sores