Evidence supporting the use of: Bioflavonoids (mixture)
For the health condition: Diabetic Retinopathy
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Bioflavonoids, a group of plant-derived compounds with antioxidant properties, have a long history of traditional use to support vascular health, including eye health. Their application in diabetic retinopathy is rooted more in traditional and empirical practice than in robust scientific validation. Historically, bioflavonoids (such as rutin, quercetin, and hesperidin) have been believed to strengthen capillaries and reduce vascular permeability, which is relevant in diabetic retinopathy—a condition characterized by damage to the retinal microvasculature due to chronic hyperglycemia. Some early studies and traditional medical practices suggested that bioflavonoids could help reduce capillary fragility and hemorrhage in diabetic patients. However, while there is a plausible biochemical rationale (antioxidant and anti-inflammatory properties, and possible inhibition of aldose reductase), high-quality clinical trials directly demonstrating efficacy in preventing or treating diabetic retinopathy are limited. A few small studies and animal models have indicated potential benefit, but systematic reviews and meta-analyses do not provide strong support for their widespread use in this context. Major diabetes and ophthalmology guidelines do not recommend bioflavonoids as a standard therapy for diabetic retinopathy. In summary, the use of bioflavonoids for diabetic retinopathy persists largely due to traditional beliefs and limited preliminary research, rather than solid scientific validation.
More about Bioflavonoids (mixture)
More about Diabetic Retinopathy
Other ingredients used for Diabetic Retinopathy
alpha-glycosyl isoquercitrinanthocyanins
astaxanthin
bilberry
black currant
blueberry
chlorella
chokeberry
turmeric
d-alpha tocopherol
flavonols
garlic bulb
ginger
grape
green tea
hesperidin
l-carnosine
lutein
lycopene
mixed carotenoids
pomegranate
quercetin
resveratrol
rutin
specialized pro-resolving mediators (SPMs)
spirulina
tocotrienols
vitamin C
vitamin D
vitamin E
zinc
ferulic acid
polyphenols
AMP-activated protein kinase (AMPK)
Apigenin
Aronia melanocarpa
Alpha-Lipoic Acid
anthocyanidins
anthocyanosides
Apocynin
Astragalin
Boswellic Acid
Benfotiamine
Bioflavonoids
Baicalin
Beta-glucogallin
Caffeic Acid
Carnosine
Cyanidin
Curcuminoid
Crocetin
Delphinidin
Dihydrolipoic Acid
Eicosapentaenoic Acid
Other health conditions supported by Bioflavonoids (mixture)
Allergies (respiratory)Arthritis
Bleeding (external)
Bruises (healing)
Bruises (prevention)
Cancer (natural therapy for)
Capillary Weakness
Cardiovascular Disease
Circulation (poor)
Colds (antiviral)
Colds (general)
Colds (prevention)
Diabetic Retinopathy
Edema
Eye Problems
Eyes (red or itching)
Eyesight (poor)
Free Radical Damage
Gastritis
Gingivitis
Hemorrhoids
Inflammation