Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Sulfur compounds have a long history of use in dermatology, especially for treating various forms of dermatitis, such as seborrheic dermatitis, acne, and scabies. The scientific basis for their use lies in sulfur’s keratolytic (skin-shedding), antibacterial, and antifungal properties. Topical sulfur preparations, usually in ointments or soaps, help to remove dead skin, decrease oiliness, and reduce microbial load on the skin. Several clinical studies and reviews support sulfur’s efficacy in mild to moderate seborrheic dermatitis and acne. For example, a review published in the Journal of Drugs in Dermatology (2019) discussed sulfur’s effectiveness in reducing symptoms and its favorable safety profile. However, high-quality randomized controlled trials specifically for dermatitis (other than acne or scabies) are limited, so most evidence is drawn from smaller studies and longstanding clinical experience. Adverse effects are generally mild and include dryness, irritation, and odor. In summary, the use of sulfur compounds for dermatitis is supported both by tradition and a moderate degree of scientific evidence, especially for seborrheic dermatitis and related skin conditions, although more rigorous studies could further clarify its role.

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