Synopsis

Source of validity: Traditional
Rating (out of 5): 2

The use of Solanaceae plants (such as nightshades, including species like Solanum nigrum, Capsicum annuum, and Atropa belladonna) for dermatitis has roots in traditional medicine systems in various cultures. For example, Solanum nigrum (black nightshade) leaves have been used in topical poultices or decoctions in folk medicine to soothe skin inflammation and treat conditions like eczema and dermatitis. Similarly, Capsicum ointments (derived from chili peppers) have a history of topical use, though more for neuropathic pain than dermatitis per se.

However, scientific validation for their use specifically in treating dermatitis is limited. There are some preclinical studies suggesting anti-inflammatory and antioxidant properties of certain Solanaceae extracts, but robust clinical trials in humans for dermatitis are scarce. Some components, such as capsaicin, can actually cause skin irritation, and toxic alkaloids present in some Solanaceae plants can be harmful if used improperly.

Overall, while the use of Solanaceae plants for dermatitis has a foundation in tradition, particularly in herbal and folk medicine contexts, the evidence base is weak and largely anecdotal. Modern clinical guidelines do not recommend Solanaceae extracts for dermatitis, and care should be taken due to potential toxicity or irritation. The evidence score reflects the limited supportive data and lack of rigorous clinical validation.

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