Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Peony (Paeonia spp.), particularly the root, has a long history of use in traditional Chinese medicine (TCM) and other East Asian medical systems, often as part of multi-herb formulations for skin conditions such as dermatitis, eczema, and other inflammatory skin diseases. The most commonly referenced species in traditional medicine are Paeonia lactiflora (white peony) and Paeonia suffruticosa (tree peony). Preparations containing peony are believed in TCM to "nourish the blood," "dispel wind," and "clear heat," which are concepts associated with reducing inflammation and itching in the context of dermatitis. Modern scientific validation for peony’s use in dermatitis is limited but emerging. Some in vitro and animal studies suggest that peony root extracts and their active constituents (such as paeoniflorin) have anti-inflammatory, immunomodulatory, and antioxidant effects, which could theoretically benefit inflammatory skin disorders. However, there is a lack of robust clinical trials directly testing peony (as a single agent) for dermatitis in humans. Most of the available clinical evidence relates to traditional multi-herb formulas that include peony among other ingredients, making it difficult to attribute effects specifically to peony. In summary, the use of peony for dermatitis is primarily justified by traditional use, supported by some preliminary laboratory research, but lacks strong direct clinical evidence.

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