Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Nigella seed (Nigella sativa), also known as black seed or black cumin, has a long history of traditional use for various skin ailments, including dermatitis. More recently, scientific studies have investigated its efficacy in treating inflammatory skin conditions. The active compound thymoquinone is thought to contribute to its anti-inflammatory and antioxidant properties. Several small clinical trials and animal studies have reported that topical applications of Nigella sativa oil may reduce symptoms of atopic dermatitis, including erythema, pruritus, and lesion severity. For example, a 2013 randomized, double-blind trial found that 20% Nigella sativa ointment was as effective as betamethasone in reducing hand eczema symptoms. Additionally, a few studies have compared Nigella sativa oil favorably to standard treatments such as hydrocortisone for mild to moderate eczema, with fewer side effects.

However, the overall quality of evidence is moderate due to small sample sizes and methodological limitations. There is a need for larger, well-designed clinical trials to confirm efficacy and establish optimal dosing and safety. Nonetheless, the accumulated evidence does provide scientific support for the use of Nigella seed in the management of dermatitis, particularly as an adjunct or alternative to topical steroids in mild cases.

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